HEMOGLOBINURIA PAROXISTICA NOCTURNA PDF

Download Citation on ResearchGate | Hemoglobinuria paroxística nocturna | Paroxysmal nocturnal hemoglobinuria is a rare acquired chronic hemolytic anemia. La hemoglobinuria paroxística nocturna (HPN) es una enfermedad clonal de las células progenitoras hematopoyéticas originada por la mutación adquirida del. TRATAMIENTO DE LA HEMOGLOBINURIA PAROXISTICA NOCTURNA CON GLOBULINA ANTILINFOCITARIA. Revista de Investigacion Clinica, 45(5).

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Gomez-Morales, Laura GutierrezG. To evaluate the effectiveness of antilymphocyte globulin therapy ALG in patients with paroxysmal nocturnal hemoglobinuria PNH.

Guía Clínica para diagnóstico y tratamiento de Hemoglobinuria Paroxística Nocturna

Six patients were included. The median age was All the patients had clinical disease consistent with PNH hemolytic hemoglibinuria with some degree of transient or persistent pancytopenia and also erythrocytes with enhanced sensitivity to complement mediated lysis in vitro, as documented by either the Ham test or the sucrose lysis assay.

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The criterion for severity was the existence of continuous hemolysis in all and transfusion requirements of two or more packed red cells per month in four cases. Two patients suffered anaphylaxis after the first administration of ALG and were withdrawn from the study.

OMIM Entry – # – PAROXYSMAL NOCTURNAL HEMOGLOBINURIA 1; PNH1

Two of the four remaining patients responded, one response was total and the other minimal. The responses were transient, and no response was seen in the follow-up of months. Antilymphocyte globulin therapy for paroxjstica nocturnal hemoglobinuria E.

Translated title of the contribution Nocrurna globulin therapy for paroxysmal nocturnal hemoglobinuria Language Spanish Pages Number of pages 5 Journal Revista de Investigacion Clinica Volume 45 Issue number 5 State Published – Externally published Yes. Keywords antilymphocyte globulin therapy paroxysmal nocturnal hemoglobinuria. Revista de Investigacion Clinica45 5 Revista de Investigacion ClinicaVol. Revista de Investigacion Clinica. Gomez-Morales and Laura Gutierrez and G.

AU – Morales-Polanco, M. AU – Gomez-Morales, E.

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Antilymphocyte globulin therapy for paroxysmal nocturnal hemoglobinuria

AU – Pizzuto-Chavez, J. PY – Y1 – N2 – Objective. Access to Document Link to publication in Scopus. Link to citation list in Scopus.